BPS2011
Pharmacology 1: Biochemical signalling
基本信息
| 学分 | 6 credit points |
|---|---|
| 开课学期 | First semester |
| 校区 | Malaysia |
| 考核构成 | Laboratory reports — 30% Workshops — 15% In class progress tests — 15% End of semester assessment — 40% |
开课安排1 条
| 教学期 | 授课方式 | 状态 |
|---|---|---|
| First semester | Teaching activities are on-campus (ON-CAMPUS) | 开课 |
以上为该校区在官方资料中登记的全部开课安排，不是汇总。同一门课可能在多个 教学期开课，也可能不同教学期的授课方式不同。
课程简介
This unit lays a foundation of knowledge about how biomolecules such as proteins, nucleotides and lipids are involved in relaying extracellular signals to the inside of the cell. An understanding of how biomolecules respond to ligands (endogenous and exogenous) to activate specific cellular responses and how these responses are linked to physiological functions, human health and drug action. The gastrointestinal system will be used as an exemplar system to investigate receptor families, signal transduction and the consequences of different types of signalling pathways within the cell.
You will continue to build on the link between a strong foundational knowledge of the physiological basis of disease (pathophysiology), and the causal connections between cell biochemistry, body function at the tissue, organ and system level and human health; how aberrant signalling may be modified through identification of appropriate protein, lipid or DNA targets (drug discovery: target identification and validation).
You will practice fundamental laboratory techniques and experimental approaches to solving biological, biochemical and physiological research questions, and how to record, interpret and communicate the outcomes of such investigations to a variety of audiences.
Topics to be covered include:
• protein synthesis, modification, trafficking and expression in the cell (and regulatory mechanisms);
• proteins as receptors, and receptor families, including: ligand-gated ion channels, G-protein coupled receptors, tyrosine kinase receptors;
• signal transduction mechanisms;
• DNA as a target;
以上为 Monash Handbook 的官方原文，版权属 Monash University，此处按本站要求转载并标注出处： 官方页面 ↗
学习成果7 条
官方原文（Learning outcomes），版权属 Monash University。
- ULO1 Explain how the structure of biomolecules influences their physiological function;
- ULO2 Explain how the interaction of a ligand or binding molecule and a receptor biomolecule effect cellular responses;
- ULO3 Compare different receptor families with regards to endogenous and exogenous ligand characteristics, and how the signal is transduced into a response via different signalling pathways;
- ULO4 Predict the effect of signalling pathway disruptions on physiological functions and human health;
- ULO5 Suggest a rational drug therapy strategy to target a disease state with known pathophysiological causes;
- ULO6 Design and safely and effectively perform an hypothesis-driven experimental approach to investigate cellular signalling processes using common biochemical and physiological techniques
- ULO7 Analyse and critically interpret experimental data and report it in written, visual and verbal formats.
教学方式与预期工作量
教学方式
Enquiry-based learning - Laboratory experiments
Online learning - Moodle discovery modules with 'check your learning' questions
Active learning - Interactive lectures and workshops
Problem-based learning - Team based workshops
预期工作量
• Twelve 2-hour online preparation modules (discovery)
• Twenty four 1-hour Applied sessions
• Six 2-hour workshops
• Six 3-hour laboratories
• Three hours of scheduled assessment
官方原文，版权属 Monash University。
先修 / 同修要求
以下先修关系按官方来源的结构化先修字段解析，原始记号：BPS1012 AND BPS1011
先修链路
按官方先修字段的原始分组展开，AND / OR 的区别保留着—— 「A 或 B」和「A 与 B」在选课时是两回事。每门课点进去可以继续往下看。
属于这些学位1 个
这门课出现在下列学位的官方结构里。反过来说：如果你读的是这些学位之一，它大概率是要修的 （必修还是选修取决于它在 Part 里的位置，点进去看结构）。
数据来源
- 数据来源
- 官方网页
handbook.monash.edu ↗ - 抓取时间
- 2026-09-13
- 可信度
- 程序抓取，未人工核实
查看官方完整描述 ↗ — 事实性字段（代码、学分、教学期、授课方式、考核权重、先修/同修/互斥关系）与 课程简介、学习成果、教学方式、预期工作量均取自官方 Handbook； 正文版权属 Monash University，此处转载并逐处标注出处。
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