MPS5103
Drug design and optimisation
基本信息
| 学分 | 6 credit points |
|---|---|
| 开课学期 | First semester |
| 校区 | Malaysia |
| 考核构成 | Final report — 30% Workshop activities — 15% In-semester tests — 55% |
开课安排1 条
| 教学期 | 授课方式 | 状态 |
|---|---|---|
| First semester | Teaching activities are on-campus (ON-CAMPUS) | 开课 |
以上为该校区在官方资料中登记的全部开课安排，不是汇总。同一门课可能在多个 教学期开课，也可能不同教学期的授课方式不同。
课程简介
This unit introduces you to pharmaceutical discovery and development, and the strategies used to optimise bioactive molecules into clinically useful drugs.
The unit will discuss the sources of bioactive molecules and the approaches used to identify small molecules that interact with a given target (hits); strategies used to optimise properties of hits to give molecules worthy of further development (leads); biological drugs; and the processes by which candidate drugs are evaluated. The unit will provide an introduction to computational modelling and discuss how computer-aided molecular modelling can be used in ligand-based and receptor-based approaches to aid drug development. Throughout the unit, you will be guided through a series of written research exercises, culminating in a comprehensive report on the design and optimisation of a contemporary drug.
Upon completing this unit, you will have a knowledge base from which you can critically evaluate the suitability of drug discovery and design approaches appropriate for different situations.
以上为 Monash Handbook 的官方原文，版权属 Monash University，此处按本站要求转载并标注出处： 官方页面 ↗
学习成果5 条
官方原文（Learning outcomes），版权属 Monash University。
- ULO1 Describe the key components and strategies of drug discovery and optimisation
- ULO2 Utilise different computational techniques to aid the design of small molecules with good affinity for biomolecular targets
- ULO3 Propose modifications to hit molecules necessary to map their structure-activity relationship (SAR), and guide hit-to-lead and lead-to-drug optimisation strategies
- ULO4 Critically evaluate different drug discovery and optimisation approaches and identify the most suitable approach for a particular situation
- ULO5 Use effective written communication skills to present informed outcomes of enquiry-based research into examples of drug design and optimisation.
教学方式与预期工作量
教学方式
Enquiry-based learning
Online learning
Peer assisted learning
Case-based teaching
Active learning
Problem-based learning
预期工作量
• 36 hours of online modules
• Twelve 2-hour workshops
• Twelve 1-hour applied sessions
• 72 hours of independent study
官方原文，版权属 Monash University。
先修 / 同修要求
官方资料未列出该课程的先修要求。
先修链路
官方资料未列出该课程的先修要求，因此没有链路可画。
属于这些学位1 个
这门课出现在下列学位的官方结构里。反过来说：如果你读的是这些学位之一，它大概率是要修的 （必修还是选修取决于它在 Part 里的位置，点进去看结构）。
数据来源
- 数据来源
- 官方网页
handbook.monash.edu ↗ - 抓取时间
- 2026-09-13
- 可信度
- 程序抓取，未人工核实
查看官方完整描述 ↗ — 事实性字段（代码、学分、教学期、授课方式、考核权重、先修/同修/互斥关系）与 课程简介、学习成果、教学方式、预期工作量均取自官方 Handbook； 正文版权属 Monash University，此处转载并逐处标注出处。
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