MPS5102
Target identification and validation
基本信息
| 学分 | 6 credit points |
|---|---|
| 开课学期 | First semester |
| 校区 | Malaysia |
| 考核构成 | Oral examinations – vivas — 35% Disease and drug dossiers — 50% Final recap and reflection — 15% |
开课安排1 条
| 教学期 | 授课方式 | 状态 |
|---|---|---|
| First semester | Teaching activities are on-campus (ON-CAMPUS) | 开课 |
以上为该校区在官方资料中登记的全部开课安排，不是汇总。同一门课可能在多个 教学期开课，也可能不同教学期的授课方式不同。
课程简介
This unit outlines the relationship between pathophysiology and the rational design and use of drugs.
You will be introduced to the physiological basis of disease, highlighting the causal connections between cell biochemistry, body function at the tissue, organ and system level, and human health. You will study the relationship between ligands (endogenous and exogenous) and the activation of specific cellular responses, and will explain how the selection of a relevant therapeutic target is based on a thorough understanding of biochemistry, physiology and pharmacology, and the impact of the disease process on optimal function.
Upon completing this unit, you will understand how aberrant signalling may be modified through identification and validation of appropriate protein, lipid or DNA targets, and be prepared to take these targets to the next stage in the process: drug design and optimisation.
以上为 Monash Handbook 的官方原文，版权属 Monash University，此处按本站要求转载并标注出处： 官方页面 ↗
学习成果6 条
官方原文（Learning outcomes），版权属 Monash University。
- ULO1 Describe the processes by which disease states can alter homeostatic and physiological functions (pathophysiology), explaining the relationship between disrupted function/s and observed signs and symptoms
- ULO2 Explain in detail how drug treatments target the pathophysiology disease states, identifying the drug target and cellular target relevant to the disease state
- ULO3 Articulate the process of target identification and validation using selected disease states as case studies, and explain how emerging technologies are integrated into the process of target identification and validation and their advantages.
- ULO4 Define the characteristics of an ideal drug target and use a systematic approach to evaluate whether exemplar therapeutics reflect these properties, proposing a rationale for why deviating from accepted drug target might be acceptable and/or necessary in certain situations
- ULO5 Use effective teamwork and collaborative skills, and research skills to develop a set of target identification and validation dossiers
- ULO6 Demonstrate oral and written communication skills appropriate for master’s students.
教学方式与预期工作量
教学方式
Peer assisted learning
Active learning
Enquiry-based learning
Research activities
Online learning
预期工作量
• 18 hours online modules (discovery)
• Twelve 3-hour workshops
• 55 hours of team-based collaborative work
• 45 hours of independent study
官方原文，版权属 Monash University。
先修 / 同修要求
官方资料未列出该课程的先修要求。
先修链路
官方资料未列出该课程的先修要求，因此没有链路可画。
属于这些学位1 个
这门课出现在下列学位的官方结构里。反过来说：如果你读的是这些学位之一，它大概率是要修的 （必修还是选修取决于它在 Part 里的位置，点进去看结构）。
数据来源
- 数据来源
- 官方网页
handbook.monash.edu ↗ - 抓取时间
- 2026-09-13
- 可信度
- 程序抓取，未人工核实
查看官方完整描述 ↗ — 事实性字段（代码、学分、教学期、授课方式、考核权重、先修/同修/互斥关系）与 课程简介、学习成果、教学方式、预期工作量均取自官方 Handbook； 正文版权属 Monash University，此处转载并逐处标注出处。
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